Mental Health
Recent studies have shown that the functioning of the gut-brain axis depends on the gut microbiota
The term gut–microbiota–brain axis is currently used to describe the complex bidirectional communication network between the gastrointestinal tract, the gut microbiota, and the central nervous system. This axis operates in both directions: psychological stress may adversely affect the composition and function of the gut microbiota, while dysbiosis may influence brain function and behavior.
Communication within the gut–microbiota–brain axis is mediated through multiple pathways, including neurotransmitters, the autonomic nervous system, the vagus nerve, cytokines produced by immune effector cells stimulated by the microbiota, and various metabolites generated by gut microorganisms.
Probiotics may exert beneficial effects on physiological functions related to the central nervous system. Probiotic strains that influence central nervous system function through modulation of the gut–brain axis are commonly referred to as psychobiotics.
Kang Y, Kang X, Cai Y. The gut microbiome as a target for adjuvant therapy in insomnia disorder. Clin Res Hepatol Gastroenterol. 2021 Nov 18;46(1):101834. doi: 10.1016/j.clinre.2021.101834
Deidda G, Biazzo M. Gut and Brain: Investigating Physiological and Pathological Interactions Between Microbiota and Brain to Gain New Therapeutic Avenues for Brain Diseases. Front Neurosci. 2021 Oct 12;15:753915. doi: 10.3389/fnins.2021.753915
Sharma H, Bajwa J. Approach of probiotics in mental health as a psychobiotics. Arch Microbiol. 2021 Dec 19;204(1):30. doi: 10.1007/s00203-021-02622-x
The Contribution of Gut Microbiota-Brain Axis in the Development of Brain Disorders
Maiuolo J, Gliozzi M, Musolino V, Carresi C, Scarano F, Nucera S, Scicchitano M, Oppedisano F, Bosco F, Ruga S, Zito MC, Macri R, Palma E, Muscoli C, Mollace V. Front Neurosci. 2021 Mar 23;15:616883. doi: 10.3389/fnins.2021.616883
NORDBIOTIC™ strains preparation
Subjects of our research in viral infections and immunity with particular emphasis on of Sars-Cov 2:
- B lactis NORDBIOTIC BI040
- B longum NORDBIOTIC BL020
- L rhamnosus NORDBIOTIC LR1100
- L casei NORDBIOTIC LC130
- L acidophilus NORDBIOTIC LA120
NORDBIOTIC™ studies are designed according to the rules of Evidence Based Medicine
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